It is possible to combine the results of several small studies to produce evidence that is stronger than that available from each study alone—a statistical method known as meta-analysis. One of four such analyses, conducted in 2006, looked at 19 studies on a total of 1,084 patients. It concluded that a third achieved an excellent reduction in seizure frequency and half the patients achieved a good reduction.
Make things yourself. While it’s extremely convenient to buy most things pre-made or pre-cooked, it always adds to the price per pound on items. Try prepping veggies ahead of time instead of buying pre-cut ones. Try making your stew meat from a chuck roast. Or, simply try to make your mayo and salad dressings at home. The simplest of things can work to cut down on your overall grocery shopping.
Bread probably isn’t the first thing that comes to mind when you think about the ketogenic diet because it’s generally full of carbs. But, if you replace your store-bought bread with a homemade keto bread recipe, it can fit seamlessly into your keto low-carb, high-fat diet. How does bread even become keto-friendly? With almond flour, a lot of eggs, cream of tartar, butter, baking soda and apple cider vinegar.
Seidelmann recently published a massive, blockbuster global study of the eating patterns of more than 447,000 people around the world. What she discovered — and what is probably not a huge surprise — is that no matter where you live or what your daily diet is like, banning entire food groups and thinking you can cheat your way into good health might work for a while, but it could also send you into an early grave.
The ketogenic diet reduces seizure frequency by more than 50% in half of the patients who try it and by more than 90% in a third of patients. Three-quarters of children who respond do so within two weeks, though experts recommend a trial of at least three months before assuming it has been ineffective. Children with refractory epilepsy are more likely to benefit from the ketogenic diet than from trying another anticonvulsant drug. There is some evidence that adolescents and adults may also benefit from the diet.
The ketogenic diet is a medical nutrition therapy that involves participants from various disciplines. Team members include a registered paediatric dietitian who coordinates the diet programme; a paediatric neurologist who is experienced in offering the ketogenic diet; and a registered nurse who is familiar with childhood epilepsy. Additional help may come from a medical social worker who works with the family and a pharmacist who can advise on the carbohydrate content of medicines. Lastly, the parents and other caregivers must be educated in many aspects of the diet for it to be safely implemented.
But even if you’re not trying to lose weight, the keto meal plans might appeal to you. By limiting sugars and processed grains, you lower your risk of type 2 diabetes. Eating an array of heart-healthy fats, like nuts, olive oil and fish, can decrease your risk of heart disease. And while some people stick to a super strict keto diet, with 75 percent of their diet coming from fat, 20 percent from protein and just five from carbs, even a less intense, modified version can help you reap the keto diet’s benefits.
This two-day keto meal plan comes from a registered dietitian who prescribes the diet for clients who are looking to reach a variety of health goals. Pegah Jalali, MS, RD, CDN, is an adjunct professor at New York University, works at the NYU Langone Comprehensive Epilepsy Center, and is a private practice dietitian at Middleberg Nutrition, a New York City health and wellness practice.
Lisa, Technically Instant Pot doesn’t recommend cooking frozen chicken breasts; however, when we cook frozen chicken breasts in the Instant Pot, we usually add an extra 3 to 5 minutes to the cooking time. For the slow cooker, you could add all the ingredients as-is (just cook the bacon on the stove top first, add the bacon fat to slow cooker, and store cooked bacon in the fridge until serving). We recommend cooking on high 3 to 4 hours or cook on low 6 to 8 hours. Let us know how it goes if you give it a try!
A lot of conflicting information has been circulated about the consumption of fat. People are sometimes concerned that adding fat to their diet will cause them to gain weight. This is not necessarily the case. Fat a neutral food. It is also satisfying. If you eat a low-fat meal, whether you have carbs or not, you will stay hungry. Fat allows you to feel full for longer. Furthermore, fat does not spike insulin and adding some healthy fat at meals will help you go longer between meals and really dip down into your fat stores to burn that fat off the body. Burning all that fat off the body is much healthier than holding onto it—which will lead to insulin resistance, diabetes, and all the dominoes that fall after that—cardiovascular disease, cancer, the list goes on and on.
Lunch: pat dry chicken and cut into cubes. Lightly (!) salt and pepper. Heat a skillet over medium heat, once hot add coconut oil and fry chicken cubes until brown from all sides. Remove chicken, and add crushed garlic, curry paste and fish sauce to pan. Stir until fragrant and remaining oil in pan and curry paste are well combined. Then add coconut milk and whisk until well combined. Simmer and reduce sauce until desired consistency (1-3 minutes). Pour sauce over chicken and sprinkle with sesame seeds. Serve with baby spinach.
There are many scenarios that can cause constipation with the ketogenic diet. Most people assume it’s a fiber issue; but it’s not that simple. You want to compare what you were doing before ketosis and after. Look at the change in vegetable fiber consumption; if you don’t have enough gut bacteria to digest all these vegetables, they will cause bloating, constipation, gas and all kinds of digestive issues. Some people can digest vegetables and others can’t. Some people can’t digest cabbage or cruciferous veggies. So, you might have to switch to less fibrous vegetables, such as various kinds of lettuce, and especially kale and beet greens, for your potassium. Electrolytes greatly help with constipation, too. If you need more support getting electrolytes, try my electrolyte powder. It helps supply the 4,700 mg a day of potassium you need, which is hard to manage without eating loads of vegetables.
For another science-based resource on ketogenic diets, I highly recommend visiting the site that Raphael Sirtoli and his team over at Break Nutrition have put together. They have good content about low carb and ketogenic diets, and they offer more information on how to kick-start a ketogenic diet, measure your ketones and there's a great post on the benefits of ketogenic diets for inflammation.
Salad — You really can’t go wrong with low-carb vegetables, especially with mixed greens as the base. Add some bacon bits, hard-boiled egg, and/or parmesan cheese for extra fat and protein. Use a homemade full-fat keto dressing or something simple like extra virgin olive oil to add even more fat. Here are some delicious keto salads you can try: Charred Veggie and Fried Goat Cheese Salad, Crispy Pork Salad, Oven Roasted Caprese Salad, and Spinach Watercress Keto Salad.
The nerve impulse is characterised by a great influx of sodium ions through channels in the neuron's cell membrane followed by an efflux of potassium ions through other channels. The neuron is unable to fire again for a short time (known as the refractory period), which is mediated by another potassium channel. The flow through these ion channels is governed by a "gate" which is opened by either a voltage change or a chemical messenger known as a ligand (such as a neurotransmitter). These channels are another target for anticonvulsant drugs.
As a result of those satiating fats required by the ketogenic diet, you may find you’re not craving snacks as much as you usually do. “I find people who follow the ketogenic diet, they’re just not as hungry, so their snack frequency comes down,” says Dina Griffin, RDN, with eNRG Performance in Littleton, Colorado. “There’s just so much fat in their diet, so they say, ‘I don’t want to eat again,’ or ‘I can’t, I’m just not hungry.’”
With intermittent fasting, the whole goal is to burn off excess fat, right? Watch how you feel when you exercise. Do you feel best when you exercise after eating or if you exercise while fasting? Watch if your legs feel heavy or if you tire too easily. Some people do well with eating first, while some love that feeling of exercising when they have fasted and having to eat afterwards.
Although many hypotheses have been put forward to explain how the ketogenic diet works, it remains a mystery. Disproven hypotheses include systemic acidosis (high levels of acid in the blood), electrolyte changes and hypoglycaemia (low blood glucose). Although many biochemical changes are known to occur in the brain of a patient on the ketogenic diet, it is not known which of these has an anticonvulsant effect. The lack of understanding in this area is similar to the situation with many anticonvulsant drugs.
Conklin's fasting therapy was adopted by neurologists in mainstream practice. In 1916, a Dr McMurray wrote to the New York Medical Journal claiming to have successfully treated epilepsy patients with a fast, followed by a starch- and sugar-free diet, since 1912. In 1921, prominent endocrinologist Henry Rawle Geyelin reported his experiences to the American Medical Association convention. He had seen Conklin's success first-hand and had attempted to reproduce the results in 36 of his own patients. He achieved similar results despite only having studied the patients for a short time. Further studies in the 1920s indicated that seizures generally returned after the fast. Charles P. Howland, the parent of one of Conklin's successful patients and a wealthy New York corporate lawyer, gave his brother John Elias Howland a gift of $5,000 to study "the ketosis of starvation". As professor of paediatrics at Johns Hopkins Hospital, John E. Howland used the money to fund research undertaken by neurologist Stanley Cobb and his assistant William G. Lennox.
"Sunflower seeds are a great snack option whether you follow a keto diet or not," says registered dietitian Katey Davidson, M.S., R.D. Although all sunflower seeds are an excellent source of healthy unsaturated fats, protein, and vitamin E, many companies use flavorings to season their products which can be high in both salt and sugar, says Davidson. She recommends Terrasoul Superfoods because they aren't flavored or salted. And with only 6 grams of carbs and 1 gram of sugar (per one 1/4 cup), you won't have to worry about these seeds throwing you out of your hard-earned ketosis. However, Davidson says you'll want to aim to eat just a handful of seeds, which is considered a serving. (Related: This keto smoothie recipe is delicious even without a ton of fruit.)
Ketogenic diets are very, very powerful, metabolically speaking and this is especially important if you take any kind of medication for blood pressure, diabetes, cholesterol or triglycerides. The amount taken of these medications will most likely need to be sharply reduced while on a ketogenic diet to avoid negative effects such as excessively low blood sugar or blood pressure.
Ketosis takes some time to get into – about two weeks of low carb eating is required for the initial adaptation. During this time there will be bouts of sluggishness, fatigue, headaches, and some gastrointestinal issues as you adapt, often referred to as “keto flu“. Proper electrolyte intake will correct most of these issues. In addition, the “diet” aspect of this ketogenic diet plan – that is, the caloric restriction – shouldn’t be worried about. Weight loss will come as your body regulates appetite as it the addiction to sugar and processed food lessens, so restricting calories during the initial two weeks isn’t recommended.
Jalali recommends that her clients work with a medical professional who is familiar with the diet to get the best results. "I do not think most of the general population would benefit from a ketogenic diet, although it can be very beneficial for some. The diet can be extremely challenging to stay compliant on long term so I find that clients who are very motivated and have a strong support system seem to be most successful."
Sweeney does not stick to a specific macronutrient balance when he begins his own ketogenic diet plan. Instead, he maintains a diet that includes no more than 50 grams of carbohydrate per day. When he goes over 0.6 on the ketone meter (a device used to measure blood for the presence of ketones) he goes up to 70 grams of carbohydrates and takes a ketone supplement.